Kafukufuku waposachedwapa wasonyeza kuti amuna omwe amalandira jakisoni wa testosterone undecanoate kwa nthawi yaitali amakhala ndi mwayi wotsatira chithandizo chawo poyerekeza ndi omwe amalandira jekeseni wa testosterone propionate waufupi.Zomwe zapezazi zikuwonetsa kufunikira kwa njira zosavuta za chithandizo cha testosterone pakuwonetsetsa kudzipereka kwa odwala kuchiza.
Kafukufukuyu, womwe udakhudzanso kuwunika kwa data kuchokera kwa amuna opitilira 122,000 ku United States, poyerekeza kuchuluka kwa amuna omwe amathandizidwa ndi testosterone undecanoate ndi omwe amathandizidwa ndi testosterone cypionate.Zotsatira zinasonyeza kuti m'miyezi yoyamba ya 6 ya chithandizo, magulu onsewa anali ndi chiwerengero chofanana chotsatira.Komabe, pamene nthawi ya chithandizo idachokera ku 7 mpaka miyezi ya 12, 8.2% yokha ya odwala omwe amalandira testosterone cypionate anapitirizabe kulandira chithandizo, poyerekeza ndi 41.9% ya odwala omwe amalandira testosterone undecanoate.
Dr. Abraham Morgenthaler, pulofesa wothandizira opaleshoni pa dipatimenti ya urology ya Beth Israel Deaconess Medical Center ku Harvard Medical School, anafotokoza tanthauzo la zomwe anapezazi.Iye anati, "Umboni ukusonyeza kuti njira zosavuta zothandizira testosterone, monga jakisoni wokhalitsa, ndizofunika kuti amuna omwe ali ndi vuto la testosterone apitirize kulandira chithandizo."Dr. Morgenthaler anagogomezera kukula kwa kuzindikira kwa kusowa kwa testosterone monga vuto lalikulu la thanzi ndipo anatsindika ubwino wambiri wathanzi umene mankhwala a testosterone angapereke, kuphatikizapo kuwongolera shuga m'magazi, kuchepetsa mafuta, kuwonjezeka kwa minofu, kusintha maganizo, kuchulukira kwa mafupa, ngakhale kuchepetsa. kuchepa kwa magazi m'thupi.Komabe, kuzindikira zopindulitsa izi zimatengera kusungabe kutsata kwamankhwala.
Kafukufukuyu, wochitidwa ndi Dr. Morgenthaler ndi anzake, adagwiritsa ntchito deta kuchokera ku database ya Verdigm, yomwe imasonkhanitsa deta yamagetsi yamagetsi kuchokera ku malo osungirako odwala kunja kwa United States.Ofufuzawa adayang'ana kwambiri amuna azaka zapakati pa 18 ndi kupitilira omwe adayambitsa jekeseni ya testosterone undecanoate kapena testosterone cypionate mankhwala pakati pa 2014 ndi 2018. Deta, yomwe idasonkhanitsidwa pakadutsa miyezi 6 mpaka Julayi 2019, idalola ochita kafukufuku kuti awone kusamalidwa kwamankhwala potengera nthawi yanthawi yake. nthawi yoikika ndi kusiya kulikonse, kusintha kwamankhwala, kapena kumalizidwa kwamankhwala oyambilira a testosterone.
Mwachindunji, kutsata chithandizo kwa gulu la testosterone undecanoate kunatanthauzidwa ngati kusiyana kwa masiku oposa 42 pakati pa tsiku lomaliza la kusankhidwa koyamba ndi tsiku loyamba la kusankhidwa kwachiwiri, kapena kusiyana kwa masiku oposa 105 pakati pa kusankhidwa kotsatira.Mu gulu la testosterone cypionate, kusatsatira kumatanthauzidwa ngati nthawi yopitilira masiku a 21 pakati pa kusankhidwa.Kuphatikiza pa kutsatiridwa, ofufuzawo adasanthula zinthu zosiyanasiyana monga kusintha kwa kulemera kwa thupi, BMI, kuthamanga kwa magazi, milingo ya testosterone, kuchuluka kwa zochitika zatsopano zamtima, komanso ziwopsezo zoyenera kuyambira miyezi 3 isanachitike jekeseni woyamba mpaka miyezi 12 chiyambireni. chithandizo.
Zotsatirazi zikuwunikira kufunikira kwa jakisoni wa testosterone wanthawi yayitali polimbikitsa kutsata kwamankhwala ndikukulitsa phindu lomwe lingakhalepo pamankhwala a testosterone.Amuna omwe ali ndi vuto la testosterone amatha kupindula kwambiri ndi njira zochiritsira zosavuta, kuonetsetsa kupitiriza ndi kulimbikitsa kudzipereka kwa nthawi yaitali kuti apititse patsogolo thanzi lawo ndi moyo wawo wonse.
Nthawi yotumiza: Jul-07-2023